INHERITED RETINAL
DISEASES
Inherited Retinal Diseases encompass a diverse group of genetic disorders that lead to progressive retinal degeneration and vision loss. These conditions, marked by their genetic complexity and variability in manifestation, present significant challenges in understanding and developing effective treatments.
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We employ a range of models, including those based on specific genetic mutations relevant to each disease, as well as others that simulate the environmental and biological factors influencing these conditions. This multifaceted approach allows us to investigate the complex interplay of genetic and external factors in each inherited retinal disease. Additionally, we focus on models that demonstrate the impact of oxidative stress on retinal cells, acknowledging its significant role in the progression of retinal dystrophies.

IN VITRO
IN VIVO


MODELS
RPE toxicity
Acute Oxidative stress models
Chronic oxidative stress model
Mitochondrial function assays
MODELS