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INHERITED RETINAL
DISEASES 

Inherited Retinal Diseases encompass a diverse group of genetic disorders that lead to progressive retinal degeneration and vision loss. These conditions, marked by their genetic complexity and variability in manifestation, present significant challenges in understanding and developing effective treatments.

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We employ a range of models, including those based on specific genetic mutations relevant to each disease, as well as others that simulate the environmental and biological factors influencing these conditions. This multifaceted approach allows us to investigate the complex interplay of genetic and external factors in each inherited retinal disease. Additionally, we focus on models that demonstrate the impact of oxidative stress on retinal cells, acknowledging its significant role in the progression of retinal dystrophies.

IN VITRO

IN VIVO

Image by National Cancer Institute
OIR tuft_cyan and magenta.tif

MODELS

RPE toxicity

Acute Oxidative stress models

Chronic oxidative stress model

Mitochondrial function assays

MODELS

NMU model

Sodium iodate model

Bright light induced models

Genetic models

Cellular functionality assays

Stargardt

Inherited Retinal Dystrophy

Usher Syndrome

Leber Congenital Amaurosis

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MediNect Bioservices Ltd is a registered company in Northern Ireland, UK

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Company Number: NI686323

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NORTHERN IRELAND
BT7 1NF

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